HPE at ISC High Performance 2026
The event for high performance computing, AI, data analytics & quantum computing.
June 22–26, 2026 | Hamburg, Germany
Booth C10
Powering AI at supercomputing speed
To stay competitive, you need to unlock the full potential of sovereign AI. Work with the leader in HPC, AI, and quantum to accelerate innovation at supercomputing speed with secure, scalable, and high-performance solutions.
Visit Booth C10 to talk with our supercomputing experts, experience the following demos, and much more.
Featured HPE sessions
Don't miss these featured HPE sessions at ISC High Performance 2026. Discover how HPE is advancing AI, supercomputing, quantum innovation, and high-performance networking to power the next era of research and enterprise transformation.
How to build a quantum supercomputer: HPE Labs
Quantum computing is no longer just theory. HPE Labs is helping to make it real. By combining today's powerful supercomputers with the potential of quantum accelerators, we're unlocking faster, smarter solutions for challenges like drug discovery, new materials research, and advanced cryptography. Discover how Labs' cutting-edge innovations are reshaping industries, paving the way for breakthroughs that will define the next generation of technology. The future is now.
Session date and time:
Wednesday, June 24, 10:00 – 11:00am
Location:
Convention Center Hall X Room 12
Aaron is a Sr. Principal Technical Product & Program manager in HPE Quantum as part of the Emergent Machine Intelligence team at HPE Labs. Aaron is also an Adjunct Associate Professor at University of Maryland, College Park in the institute for Physical Science and Technology (IPST).
Prior to joining HPE, Aaron was a Sr. Scientist & Technical Program Manager in the NASA Ames Quantum Artificial Intelligence Laboratory (QuAIL) leading R&D in the contractor teams across quantum computing, machine learning, data science and nanodevices. Aaron also served as Director of Technical Product Management at D-Wave, where he led development of the D-Wave 2X, D-Wave 2000Q hardware and software features, open-source software, as well as several research projects exploring algorithms, benchmarking, and development of quantum computers in optimization, machine learning and materials science applications.
Aaron performed post-doctoral research at the National Institute of Standards and Technology and Lawrence Livermore National Laboratory. Aaron earned his Ph.D. in Applied Mathematics and Scientific Computation at the University of Maryland.
His current interests are in building a quantum supercomputer, via deep integration between classical high-performance computing, multiple quantum hardware modalities and AI techniques to enable the next generation of scientific computing.
Aaron Lott, PhD
Sr. Principal Technical Product & Program Manager, HPE Labs
HPE Juniper Data Center Networking for AI & HPC
AI and HPC are changing how data centers are built—driving new requirements for bandwidth, latency, power efficiency, and operational consistency. This session starts with a high-level introduction to the HPE Juniper data center networking portfolio and a clear framework for scale‑out (front‑end and back‑end), scale‑across, and scale‑up networking. We'll then focus on a more in-depth discussion on AI data center fabrics and how we enable higher‑performance compute domains. We'll show how purpose‑built platforms and Junos OS capabilities pair with Apstra Data Center Director–driven automation, visibility, and lifecycle operations—covering items like end‑to‑end fabric insights and operational enhancements for AI environments.
Session date and time:
Wednesday, June 24, 3:00 – 4:00pm
Location:
Convention Center Hall X Room 12, 10:00 – 11:00am
Supercharge your AI factory: HPE AI Factory
Organizations aim to maximize returns from investments in AI Factory GPU clusters for AI model training, tuning, inferencing, and mixed HPC workloads. This requires equitable, secure, and performant resource access, with self-service options for agility and tight cost monitoring. HPE offers an adaptable full-stack AI platform with control plane and workflow automations, enabling IT managers and service administrators to implement and scale these processes as AI workloads grow.
Session date and time:
Tuesday, June 23, 3:00 – 4:00pm
Location:
Convention Center Hall X Room 12
Linda brings together AI, HPC, and business strategy, helping organisations cut through the growing complexity of digital transformation. She specialises in early customer engagement, acting as a subject matter expert and driving business development initiatives.
Her work focuses on helping organisations move beyond simply adopting AI to achieving meaningful transformation. She recognises that AI impacts each function differently, and focuses on aligning stakeholders, strengthening foundations, and embedding change that sticks.
Linda brings 17 years of experience delivering customer-led technology and transformation, combining a pragmatic, commercially grounded approach with the agility required to succeed in a rapidly evolving technology landscape.
Linda Coule
HPC & AI Business Development Manager, Hewlett Packard Enterprise
ISC26 Vendor Showdown 2
Session date and time:
Tuesday, June 23, 2026, 11:15am – 12:55pm
Jim Lujan's presentation time: 12:28 – 12:38pm
Location:
Convention Center Hall 4
Jim Luján is Vice President of Leadership Systems Engineering at Hewlett Packard Enterprise, where he leads the global engineering organization responsible for delivering leadership-class supercomputing systems for HPC and AI, spanning architecture, hardware engineering, systems integration, deployment, and lifecycle support.
A long-time leader in high performance computing, Jim previously served as ASC Program and Project Director for the High Performance Computing Division at Los Alamos National Laboratory. Over his career, he has worked across Cray, SGI, LANL, and HPE on the development and deployment of advanced supercomputing systems, including Trinity, Crossroads, Venado, supporting national security, scientific research, and next-generation AI workloads.
Jim Luján
VP, Vice President of Leadership Systems Engineering, HPE
ISC26 HPC–AI demos
At-scale AI deployments for neo-clouds: NVIDIA Vera Rubin NVL72 by HPE
Learn about NVIDIA Vera Rubin NVL72 by HPE, a fully integrated, rack scale AI system unifying 72 NVIDIA Rubin GPUs and 36 NVIDIA Vera CPUs into a single NVLink domain for extreme training and high-volume inference. Beyond performance, HPE brings five decades of liquid cooling expertise, and comprehensive HPE Services spanning design, deployment, performance engineering, and global lifecycle support—enabling organizations to stand up and operate dense AI factories with speed, predictability, and confidence.
Unlock the future of converged HPC and AI: NVIDIA GB200 NVL4 by HPE
This rack-scale system is ideal for converged HPC and AI workloads. Powered by the NVIDIA GB200 superchip, each 1U compute tray combines 4 NVIDIA B200 GPUs with two NVIDIA Grace CPUs, delivering powerful acceleration and FP64 performance. With up to 34 trays in a 48U MGX rack, the system scales to 136 GPUs per rack for exceptional density. Advanced liquid cooling from HPE and HPE Performance Cluster Manager complement the solution.
HPE ProLiant Compute XD230
The HPE ProLiant Compute XD230 server is purpose-built for HPC workloads, delivering exceptional performance and efficiency. Powered by 2x Intel Xeon 6 processors with P-cores and advanced MRDIMMs, it achieves up to 8800 MT/s memory speed. Optional Direct Liquid Cooling enhances sustainability and performance. HPE iLO and Silicon Root of Trust ensure security, while HPE Performance Cluster Manager enables comprehensive system monitoring and management.
AI training, tuning, and inference: HPE ProLiant Compute XD685 with AMD
This demo showcases the AMD Instinct MI355X Platform, featuring eight GPUs on a Universal Base Board (UBB) form factor. This platform is supported by HPE ProLiant Compute XD685 in a 5U liquid cooled chassis. With exceptional efficiency and performance, the platform excels at training massive AI models, high-speed AI inference, and tackling the most complex computational challenges—from scientific simulations to large-scale data processing and advanced modeling.
The future of supercomputing: HPE Cray Supercomputing GX5000
This demo showcases the AMD Instinct MI355X Platform, featuring eight GPUs on a Universal Base Board (UBB) form factor. This platform is supported by HPE ProLiant Compute XD685 in a 5U liquid cooled chassis. With exceptional efficiency and performance, the platform excels at training massive AI models, high-speed AI inference, and tackling the most complex computational challenges—from scientific simulations to large-scale data processing and advanced modeling.
Discover the foundation of HPE's next generation of supercomputers—designed to deliver unprecedented performance density for organizations tackling the world’s most complex challenges. This compute rack sets a new standard in unified high-performance computing (HPC) and AI infrastructure, offering up to 81,920 CPU cores per rack or 384 GPU dies per rack. Whether advancing scientific discovery or achieving ambitious business objectives in energy companies, this supercomputing technology is engineered to enable the next breakthrough.
HPE Cray Supercomputing GX350a accelerated blade
HPE Cray Supercomputing GX350a Accelerated Blade with one AMD Venice SP7 600-watt CPUs with up to 256 cores per CPU and four AMD Instinct MI430X series GPUs—a new MI400 Series accelerator engineered specifically forAI and is a great solution if you need a universal compute engine for mixed-precision computing with AMD CPUs and GPUs—like the recently announced Discovery supercomputer of Oak Ridge National Laboratory. See how up to 28 of these blades can be configured per compute rack—enabling up to 112 AMD MI430X accelerators per rack.
HPE Slingshot Interconnect 400
Is your HPC networking solution able to meet your converged workload needs for today and tomorrow? See the HPE Slingshot Interconnect 400—now available for the HPE Supercomputing GX5000 platform—with 400 Gbps and also as a TOR switch with PCIe NICs, ready to power the world's exascale systems. HPE Slingshot provides a modern, high-performance interconnect that delivers reduced latency, improved sustained bandwidth, and reliability while managing costs.
How to build a quantum supercomputer: HPE Labs
This demo shows how quantum computing is no longer just theory and how HPE Labs is helping to make it real. By combining today's powerful supercomputers with the potential of quantum accelerators, you will learn how we are helping to unlock faster, smarter solutions for challenges like drug discovery, new materials research, and advanced cryptography. Discover how HPE Labs cutting-edge innovations are reshaping industries, paving the way for breakthroughs that will define the next generation of technology. The future is now.
HPE Cray Supercomputing Storage Systems K3000
Discover the next generation of all-flash supercomputing storage, powered by cutting-edge Distributed Asynchronous Object Storage (DAOS) software. Fully integrated and factory-built, the HPE Cray SC Storage Systems K3000 utilize HPE ProLiant DL360 Gen12 storage servers, delivering scalability to hundreds of millions of input/output operations per second. Designed for maximum AI acceleration, the embedded DAOS software integrates seamlessly with leading AI frameworks such as PyTorch and TensorFlow.
HPE Cray Supercomputing Storage Systems
Are you struggling with performance or scalability barriers for the shared file system of your large compute clusters supporting your HPC and AI workloads with high density servers? Join this demo to learn how the world's leading supercomputing sites have successfully addressed those challenges.
Direct liquid cooling delivered reliably at scale
As IT systems expand to meet the requirements of growing data and AI workloads, traditional air cooling will soon be unable to support the power needs of CPUs and GPUs drawing over 500 watts. Hear how HPE expertise in liquid cooling and our leadership portfolio span from the edge to exascale—as a culmination of over five decades of experience and innovation. Explore our HPE industry-first 100% fanless liquid cooling systems architecture and learn how it can help you achieve your performance, energy efficiency, and sustainability goals.
HPE AI factory sovereign
Organizations aim to maximize returns from investments in AI Factory GPU clusters for AI model training, tuning, inferencing, and mixed HPC workloads. This requires equitable, secure, and performant resource access, with self-service options for agility and tight cost monitoring. HPE offers an adaptable full-stack AI platform with control plane and workflow automations, enabling IT managers and service administrators to implement and scale these processes as AI workloads grow.
High performance computing software
The HPC software portfolio from HPE is optimized for HPE Cray Supercomputing infrastructure, offering customers a robust foundation to run diverse workloads. The portfolio solutions enable system management, workload management and orchestration, compute environment enhancements, software development, & more.
HPE Alletra Storage MP X10000
HPE Alletra Storage MP X10000 is a next-generation, software-defined, scale-out data system that delivers high-performance object and file storage services, data intelligence services, and an architecture designed for exabyte-scale capacities to accelerate time-to-value from data-intensive workloads including active data lakes, digital repositories, and modern data protection. The X10000 is managed through the HPE GreenLake cloud, which uniquely enables simplified and unified cloud management of HPE’s block, file, and object services, allowing enterprises to optimize their hybrid estate to take full advantage of AI.
Data Center Networking for AI Training and Inference
HPE Networking portfolio for AI data centers includes switching, routing, security, and management and automation. The solution delivers open, secure, reliable, high-performance networks for AI training, inference, and AIaaS, offering design flexibility and simplified management and operations. HPE Juniper Networking was named a Leader in the 2025 Gartner Magic Quadrant for Data Center Switching and ranked #2 for AI Ethernet Fabric Buildout in the 2025 Gartner Critical Capabilities.
AMD Helios AI Rack by HPE (Naming not final) Virtual Rack
"Helios" is the first rack-scale AI reference design from AMD, built fully on the Open Rack Wide (ORW) standard developed by Meta within the Open Compute Project. It combines 72 AMD Instinct™ MI450 Series GPUs, AMD EPYC™ CPUs, and AMD Pensando™ DPUs along with other leading components in an open, double-wide ORW rack. HPE provides a new HPE Juniper Networking scale-up Ethernet switch and software designed specifically for the AMD "Helios" AI rack-scale architecture and a proven ecosystem of HPE Services.
HPE ProLiant Compute DL380a
Meet the HPE ProLiant DL380, a server with superior AI fine tuning and inferencing for large workloads with ultra scalable GPU acceleration.
Content tracks include
Sovereign AI
Confidently grow your Sovereign AI initiatives to power innovation and unlock economic growth with HPE—from from turnkey speed and sovereign data control to massive, at‑scale deployments.
Exascale computing
Accelerate scientific discovery and bridge the worlds of supercomputing, cloud, and the datacenter by enabling straightforward execution of cloud-like and converged workloads in a supercomputing environment.
Quantum computing
The road to quantum advantage starts with supercomputing—and HPE helps lead the way. Built on decades of HPC leadership, learn how HPE is turning quantum theory into practical systems that accelerate research, enable adoption, and speed productization.
Rack-Scale systems
The portfolio of rack-scale systems from HPE is optimized for large-scale AI deployments, AI factories, and converged HPC/AI workloads. Learn how these high-density systems come with direct liquid cooling from HPE, and are backed by the proven ecosystem of HPE Services so you can deploy rapidly and operate predictably anywhere in the world.
Liquid Cooling
HPE liquid cooling unlocks higher supercomputer density and peak performance—so you can scale faster without thermal limits. Find out ways to cut energy and push more compute per watt with proven liquid‑cooled systems built for HPC and AI.
Storage
Skillfully engineered systems to help meet the demanding input/output requirements of supercomputers and HPC clusters in a very efficient way. The confluence of AI with traditional simulations requires new storage systems.
Platinum Sponsor of Women in HPC
Women in HPC is the only international organization working to improve equity, diversity and inclusion in High Performance Computing. And at HPE, we know that our greatest strengths come from the people who make up our team. So, for us, diversity, equity and inclusion are ingrained in who we are today because we know it's what will get us to tomorrow. That's why HPE is proud to be a Women in HPC Sponsor at ISC High Performance 2026. They have a full week of activities planned, and we're looking forward to partnering with them once again.