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HPE DDR5 Smart Memory QuickSpecs

Shape the Future of QuickSpecs - Your Input Matters

Table of Contents

Table of Contents

    As CPU core counts continue to increase, bandwidth per core cannot continue to scale with DDR4. New memory architectures are required to meet next-generation bandwidth per core requirements in x86 CPUs.

    As CPU core counts increase, DDR5 is designed to deliver higher bandwidth delivered to systems. DDR5 is the latest evolution in DRAM, delivering an extensive list of new features designed to increase reliability, availability, and serviceability (RAS). Reduce power; and dramatically improve performance – all features that modern data centers require.

    Overview

    HPE DDR5 Smart Memory

    Advanced workloads resulting from rapidly expanding datasets and compute-intensive applications have fueled processor core count growth which will be bandwidth-starved by current DDR4 DRAM technology over time. DDR5, the most technologically advanced DRAM to date, will enable the next generation of server workloads by delivering as much as an 85% increase in memory performance. DDR5 doubles memory density while improving reliability at a time when data center system architects seek to supply rapidly growing processor core counts with increased memory bandwidth and capacity.


    The need for higher bandwidth and density has been posing a significant challenge for the tech industry, and DDR5 is the new standard that is expected to meet these requirements for years to come.


    HPE DDR5 Smart Memory delivers great performance, reliability, and efficiency. Our large selection of server memory solutions provides the compatibility, capacity and bandwidth you need to productively manage your expanding workload with HPE ProLiant Gen11 servers, Apollo family servers, Synergy systems, and Blade systems.


    As workloads grow and data center trends such as server virtualization, cloud computing, and the use of large database applications increase the need for higher-capacity memory with greater uptime, the quality and reliability of DRAM become ever more important. HPE Smart Memory goes through additional rigorous qualification and testing processes that unlock extended memory performance features available only with HPE Gen11 servers. This extensive testing ensures that HPE server memory is completely compatible with and optimized for HPE servers.

    Image 1

    What's New

    • − HPE DDR5 Smart Memory 5600 MT/s memory supported on HPE Gen11 Intel® based servers

    Models

    Registered Memory Kits – Intel® based Servers

    HPE 16GB (1x16GB) Single Rank x8 DDR5-4800 CAS-40-39-39 EC8 Registered Smart Memory Kit

    P43322-B21

    HPE 16GB (1x16GB) Single Rank x8 DDR5-4800 CAS-40-39-39 EC8 Registered Smart Memory Kit

    P43322-K21

    HPE 32GB (1x32GB) Dual Rank x8 DDR5-4800 CAS-40-39-39 EC8 Registered Smart Memory Kit

    P43328-B21

    HPE 32GB (1x32GB) Dual Rank x8 DDR5-4800 CAS-40-39-39 EC8 Registered Smart Memory Kit

    P43328-K21

    HPE 64GB (1x64GB) Dual Rank x4 DDR5-4800 CAS-40-39-39 EC8 Registered Smart Memory Kit

    P43331-B21

    HPE 64GB (1x64GB) Dual Rank x4 DDR5-4800 CAS-40-39-39 EC8 Registered Smart Memory Kit

    P43331-K21

    HPE 96GB (1x96GB) Dual Rank x4 DDR5-4800 CAS-46-45-45 EC8 Registered Smart Memory Kit

    P66675-B21

    HPE 128GB (1x128GB) Dual Rank x4 DDR5-4800 CAS-40-39-39 EC8 Registered Smart Memory Kit

    P69974-B21

    HPE 128GB (1x128GB) Dual Rank x4 DDR5-4800 CAS-40-39-39 EC8 Registered Smart Memory Kit

    P69974-K21

    HPE 256GB (1x256GB) Octal Rank x4 DDR5-4800 CAS-46-39-39 EC8 Registered 3DS Smart Memory Kit

    P43337-K21

    HPE 256GB (1x256GB) Quad Rank x4 DDR5-4800 CAS-60-52-52 EC8 Registered 3DS Smart Memory Kit

    P90550-B21

    HPE 16GB (1x16GB) Single Rank x8 DDR5-5600 CAS-46-45-45 EC8 Registered Smart Memory Kit

    P64705-B21

    HPE 16GB (1x16GB) Single Rank x8 DDR5-5600 CAS-46-45-45 EC8 Registered Smart Memory Kit

    P64705-K21

    HPE 32GB (1x32GB) Dual Rank x8 DDR5-5600 CAS-46-45-45 EC8 Registered Smart Memory Kit

    P64706-B21

    HPE 32GB (1x32GB) Dual Rank x8 DDR5-5600 CAS-46-45-45 EC8 Registered Smart Memory Kit

    P64706-K21

    HPE 64GB (1x64GB) Dual Rank x4 DDR5-5600 CAS-46-45-45 EC8 Registered Smart Memory Kit

    P64707-B21

    HPE 64GB (1x64GB) Dual Rank x4 DDR5-5600 CAS-46-45-45 EC8 Registered Smart Memory Kit

    P64707-K21

    HPE 96GB (1x96GB) Dual Rank x4 DDR5-5600 CAS-46-45-45 EC8 Registered Smart Memory Kit

    P64708-B21

    HPE 96GB (1x96GB) Dual Rank x4 DDR5-5600 CAS-46-45-45 EC8 Registered Smart Memory Kit

    P64708-K21

    HPE 128GB (1x128GB) Dual Rank x4 DDR5-5600 CAS-46-45-45 EC8 Registered Smart Memory Kit

    P69976-B21

    HPE 256GB (1x256GB) Quad Rank x4 DDR5-4800 CAS-60-52-52 EC8 Registered 3DS Smart Memory Kit

    P90554-B21

    HPE 16GB (1x16GB) Single Rank x8 DDR5-6400 CAS-52-52-52 EC8 Registered Smart Memory Kit

    P69726-B21

    HPE 16GB (1x16GB) Single Rank x8 DDR5-6400 CAS-52-52-52 EC8 Registered Smart Memory Kit

    P69726-K21

    HPE 32GB (1x32GB) Dual Rank x8 DDR5-6400 CAS-52-52-52 EC8 Registered Smart Memory Kit

    P69727-B21

    HPE 32GB (1x32GB) Dual Rank x8 DDR5-6400 CAS-52-52-52 EC8 Registered Smart Memory Kit

    P69727-H21

    HPE 32GB (1x32GB) Dual Rank x8 DDR5-6400 CAS-52-52-52 EC8 Registered Smart Memory Kit

    P69727-K21

    HPE 64GB (1x64GB) Dual Rank x4 DDR5-6400 CAS-52-52-52 EC8 Registered Smart Memory Kit

    P69728-B21

    HPE 64GB (1x64GB) Dual Rank x4 DDR5-6400 CAS-52-52-52 EC8 Registered Smart Memory Kit

    P69728-H21

    HPE 64GB (1x64GB) Dual Rank x4 DDR5-6400 CAS-52-52-52 EC8 Registered Smart Memory Kit

    P69728-K21

    HPE 96GB (1x96GB) Dual Rank x4 DDR5-6400 CAS-52-52-52 EC8 Registered Smart Memory Kit

    P69729-B21

    HPE 96GB (1x96GB) Dual Rank x4 DDR5-6400 CAS-52-52-52 EC8 Registered Smart Memory Kit

    P69729-H21

    HPE 96GB (1x96GB) Dual Rank x4 DDR5-6400 CAS-52-52-52 EC8 Registered Smart Memory Kit

    P69729-K21

    HPE 128GB (1x128GB) Dual Rank x4 DDR5-6400 CAS-52-52-52 EC8 Registered Smart Memory Kit

    P69730-B21

    HPE 128GB (1x128GB) Dual Rank x4 DDR5-6400 CAS-52-52-52 EC8 Registered Smart Memory Kit

    P69730-H21

    HPE 128GB (1x128GB) Dual Rank x4 DDR5-6400 CAS-52-52-52 EC8 Registered Smart Memory Kit

    P69730-K21

    HPE 256GB (1x256GB) Quad Rank x4 DDR5-6400 CAS-60-52-52 EC8 Registered 3DS Smart Memory Kit

    P73447-B21

    Unregistered Memory Kits – Intel® based Servers

    HPE 16GB (1x16GB) Single Rank x8 DDR5-4800 CAS-40-39-39 Unbuffered Standard Memory Kit

    P64336-B21

    HPE 32GB (1x32GB) Dual Rank x8 DDR5-4800 CAS-40-39-39 Unbuffered Standard Memory Kit

    P64339-B21

    Models

    Registered Memory Kits – AMD based Servers

    HPE 16GB (1x16GB) Single Rank x8 DDR5-4800 CAS-40-39-39 EC8 Registered Smart Memory Kit

    P50309-B21

    HPE 32GB (1x32GB) Dual Rank x8 DDR5-4800 CAS-40-39-39 EC8 Registered Smart Memory Kit

    P50311-B21

    HPE 64GB (1x64GB) Dual Rank x4 DDR5-4800 CAS-40-39-39 EC8 Registered Smart Memory Kit

    P50312-B21

    HPE 96GB (1x96GB) Dual Rank x4 DDR5-4800 CAS-46-45-45 EC8 Registered Smart Memory Kit

    P66676-B21

    HPE 128GB (1x128GB) Dual Rank x4 DDR5-4800 CAS-40-39-39 EC8 Registered Smart Memory Kit

    P69982-B21

    HPE 256GB (1x256GB) Quad Rank x4 DDR5-4800 CAS-60-52-52 EC8 Registered 3DS Smart Memory Kit

    P90552-B21

    HPE 16GB (1x16GB) Single Rank x8 DDR5-6400 CAS-52-52-52 EC8 Registered Smart Memory Kit

    P64984-B21

    HPE 32GB (1x32GB) Dual Rank x8 DDR5-6400 CAS-52-52-52 EC8 Registered Smart Memory Kit

    P64985-B21

    HPE 64GB (1x64GB) Dual Rank x4 DDR5-6400 CAS-52-52-52 EC8 Registered Smart Memory Kit

    P64986-B21

    HPE 96GB (1x96GB) Dual Rank x4 DDR5-6400 CAS-52-52-52 EC8 Registered Smart Memory Kit

    P64987-B21

    HPE 128GB (1x128GB) Dual Rank x4 DDR5-6400 CAS-52-52-52 EC8 Registered Smart Memory Kit

    P64988-B21

    HPE 256GB (1x256GB) Quad Rank x4 DDR5-6400 CAS-60-52-52 EC8 Registered 3DS Smart Memory Kit

    P73446-B21

    Notes:

    − The -B21 memory SKUs shown in this document are to be used when ordering stand-alone memory only. For each -B21 SKU, there is a corresponding -F21 SKU which is to be used when configuring servers with integrated memory DIMMs.

    − Memory DIMM availability for a specific server platform is dependent upon completion of certification testing.

    − Memory compatibility may vary or be limited within a specific server family depending upon the specific configuration being requested. Because each server environment and requirements can vary, memory compatibility is based not only upon the server family, but may also be affected by the amount and type of additional hardware options installed within a specific server configuration. For this reason, some HPE memory DIMMs may be qualified for a server model or family and yet occasionally not be supported with limited configurations within that server family.

    − Please consult with the HPE server QuickSpecs or your HPE representative if you have any questions regarding memory compatibility with a specific HPE server configuration.

    Understanding Memory Speed Limitations

    Server memory speed will determine the rate at which the CPU can process data. The higher the clock rating on the memory, the faster the system can read and write information from the memory. All memory is rated at a specific data rate - stated in mega transfers per second (MT/s) - which is the maximum data bandwidth that the memory supports.


    In every case the maximum speed capability of the memory system is governed by the combination of the CPU and any other DIMMs installed on the server. If higher speed DIMMs are installed with a CPU that only supports a lower memory speed, the DIMMs will only run at the (lower) memory speed supported by the processor. Likewise, if memory

    DIMMs are mixed with slower DIMMs within a server, all DIMMs will run at a slower memory speed.

    XXXXXX-X21 is SKU designation formed by a common six-digit part number and a -X21 suffix that identifies a SKU that is available across multiple server family lines. Refer to the table below to find the SKU suffix that applies to the specific server product line this option can be ordered with.

    -B21

    -H21

    -K21

    COMPUTE Server Line

    SPECIALIZED COMPUTE Server Line

    STORAGE Line

    HPE Cloudline CL2100/CL2200/CL2800/CL3100/CL4100/CL5200/CL5800 Servers

    HPE Composable Cloud for ProLiant DL

    HPE ProLiant BL460c/BL660c Servers

    HPE ProLiant DL20/DL160/DL180 Servers

    HPE ProLiant DL325/DL360/DL380/DL385/DL560/DL580 Servers

    HPE ProLiant DX360/DX380 Servers

    HPE ProLiant MicroServer

    HPE ProLiant for Microsoft Azure Stack

    HPE ProLiant ML30/ML110/ML350 Servers

    HPE Synergy 480/660 Systems

    HPE ProLiant DX170r/DX190r, DX2000 Servers

    HPE ProLiant DX560 Gen10 server

    HPE ProLiant DX4200 Gen10 server

    HPE Apollo 35/40/70 Systems

    HPE Apollo 2000/6000 Servers

    HPE XL170r/XL190r/XL270d (Apollo 6500) Gen10 Server for BlueData Software

    HPE Converged System 300/500/700/750

    HPE Edgeline Systems and Servers

    HPE Integrity BL860c i6/BL870c i6/BL890c i6 Server Blades

    HPE Integrity MC990 X Server

    HPE Integrity rx2800 i6 Server

    HPE Integrity Superdome

    HPE SGI 8600 System

    HPE Solutions for SAP HANA (TDI)

    HPE Apollo 4200 Gen9/Gen10 Servers

    HPE Apollo 4200 Gen10 LFF Server for BlueData Software

    HPE Apollo 4510 Gen10 System

    HPE D2220sb/D2500sb Storage Blade

    HPE D3000/D6020/D8000 Disk Enclosures

    HPE Scalable Object Storage with Scality RING

    HPE SimpliVity 2600

    HPE SimpliVity 325/380 Gen10

    HPE Storage File Controllers

    HPE StoreEasy 1460/1560/1650/1660/1860


    Disclaimer: This may not be a complete listing of applicable servers

    Standard Features

    What is HPE Smart Memory?

    HPE Smart Memory uniquely optimizes memory performance on HPE ProLiant Rack and Tower servers, Apollo family servers, Blade systems, and Synergy systems. Authenticated HPE Smart Memory supports extended memory performance in the competitive landscape and provides customers with service enhancement through HPE Active Health Systems and other HPE proprietary software.


    Quality and Performance

    HPE Smart Memory undergoes a rigorous qualification process to provide customers with the highest server memory quality options. Its performance is tested and optimized for HPE servers, supporting unique features only available with HPE servers and systems. In addition, it enhances memory throughput up to 23% and achieves an improvement in latency of up to 25%.


    HPE Active Health System

    HPE Smart Memory works in conjunction with the HPE Active Health System which monitors changes to the server hardware configuration to enable lifecycle monitoring of memory health status. Having insight into memory-related service events will shorten problem diagnosis and deliver rapid resolutions when failures occur. Whereas the pre-failure alert simply notifies the administrator of an impending failure, HPE Smart Memory can provide rich insight into memory-related events like multi-bit errors or configuration issues.


    Reporting Correctable memory errors

    Beginning with the HPE Gen10 Plus server generation, the server ROM will provide an option that allows users to control the RAS policies, (including the ability to expose corrected memory errors to the OS and allow it to log them which may make them visible to the user). This new ROM option may be set to either “Firmware First” or “OS First” mode.


    Firmware First Mode

    When in Firmware First Mode (default), the BIOS will implement RAS features as before, to monitor corrected errors and log an event for any cases where the customer needs to act on corrected errors. The OS will not monitor, and log corrected errors.


    Operating System (OS) First Mode

    In OS First Mode, corrected errors are unmasked to the OS and the OS will control the policy for logging corrected errors. With some operating systems, while in OS First mode, corrected errors are unmasked to the OS and the OS will control the policy for logging corrected errors. Additionally, the OS may be able to create its own protection from these events by triggering a Page Retire, or other OS level mitigation. When these events happen, they are not deemed to be a trigger for a service action.


    With the understanding that corrected memory errors are an expected and natural occurrence and that no action is required based on OS logging of corrected errors (unless the BIOS has also logged an event – which would also occur in the “Firmware First” mode), HPE recommends that this option is left in its default “Firmware First” setting.


    However, for customer installations which choose to configure this option for “OS First” mode, no service action should be triggered based solely on the OS logging of corrected memory errors. Service action should only occur if the errors are logged to the Integrated Management Log (IML) by the BIOS.


    Other Resources

    For the latest updates on HPE Server Options, visit: http://www.hpe.com/us/en/servers/memory.html

    For more information on HPE Persistent Memory options, visit: https://www.hpe.com/us/en/servers/persistent-memory.html

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    HPE Managed Services | HPE


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    https://www.hpe.com/services/techcare


    HPE Lifecycle Services

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    • − HPE Firmware Update Analysis Service: Recommendations for firmware revision levels for selected HPE products, considering the relevant revision dependencies within your IT environment.
    • − HPE Firmware Update Implementation Service: Implementation of firmware updates for selected HPE server, storage, and solution products, considering the relevant revision dependencies within your IT environment.
    • − Implementation assistance services: Highly trained technical service specialists to assist you with a variety of activities, ranging from design, implementation, and platform deployment to consolidation, migration, project management, and onsite technical forums.
    • − HPE Service Credits: Access to prepaid services for flexibility to choose from a variety of specialized service activities, including assessments, performance maintenance reviews, firmware management, professional services, and operational best practices.

    Notes: To review the list of Lifecycle Services available for your product go to: https://www.hpe.com/services/lifecycle

    For a list of the most frequently purchased services using service credits, see the HPE Service Credits Menu


    Other Related Services from HPE Services

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    An option available with HPE Complete Care Service and HPE Tech Care Service and applies only to Disk or eligible SSD/Flash Drives replaced by HPE due to malfunction.


    Consult your HPE Sales Representative or Authorized Channel Partner of choice for any additional questions and service options.


    Parts and Materials

    HPE will provide HPE-supported replacement parts and materials necessary to maintain the covered hardware product in operating condition, including parts and materials for available and recommended engineering improvements.


    Parts and components that have reached their maximum supported lifetime and/or the maximum usage limitations as set forth in the manufacturer's operating manual, product QuickSpecs, or the technical product data sheet will not be provided, repaired, or replaced as part of these services.


    How to Purchase Services

    Services are sold by Hewlett Packard Enterprise and Hewlett Packard Enterprise Authorized Service Partners:

    • − Services for customers purchasing from HPE or an enterprise reseller are quoted using HPE order configuration tools.
    • − Customers purchasing from a commercial reseller can find services at https://ssc.hpe.com/portal/site/ssc/

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    The result: greater operational efficiency, lower TCO, and faster AI delivery—all from one unified, intelligent platform built for today’s hybrid enterprise.

    Summary of Changes

    Date

    Version History

    Action

    Description of Change

    06-Apr-2026

    Changed

    Overview section was updated.

    Added

    Registered Memory Kits – Intel® based Servers SKUs.

    Removed

    Obsolete SKUS.

    05-Jan-2026

    Changed

    Overview section was updated.

    Removed

    Fast Fault Tolerance Factory Setting obsolete SKU.

    28-Jul-2025

    Changed

    Update survey link.

    05-May-2025

    Changed

    Overview, Models Section was Updated

    03-Mar-2025

    Changed

    Models Section was updated and SKU P73446-B21 was added

    24-Feb-2025

    Changed

    Overview Section was updated, and obsolete SKUs were removed

    04-Nov-2024

    Changed

    Overview Section was updated, and obsolete SKUs were removed

    07-Oct-2024

    Changed

    Overview Section was updated

    06-May-2024

    Changed

    Overview Section was updated

    14-Dec-2023

    Changed

    Model Section, SKUs, Service and Support Section were updated.

    05-Sep-2023

    Changed

    QuickSpecs name was updated

    06-Feb-2023

    Changed

    Model Section and SKUs were updated

    10-Jan-2023

    Changed

    Overview Section was updated

    10-Nov-2022

    New

    New QuickSpecs.

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