Compute servers HPE ProLiant Compute
Propel your business forward with next-gen HPE ProLiant Compute servers, purpose-built for today's hybrid world. Modernize confidently with built-in security, AI-driven automation, and energy-efficient performance. Simplify operations, reduce risks, and gain real-time value from edge to cloud.
Benefits of HPE ProLiant Compute
Our customers
Empower your enterprise with next-gen compute and virtualization solutions
Modernize aging infrastructure and take control of virtualization with a secure, efficient foundation built for evolving enterprise workloads.
See how HPE ProLiant Compute Gen12 and HPE Morpheus Software—VM essentials help simplify virtualization, reduce costs, and power workloads from VDI to AI.
Explore the HPE ProLiant Compute portfolio
- AI servers
- Rack
- Tower
- Edge servers
 HPE ProLiant Compute DL380a Gen12 |  HPE ProLiant Compute DL384 Gen12 |  HPE ProLiant Compute DL394 Gen12 |  HPE ProLiant Compute XD685 | |
|---|---|---|---|---|
| Workloads | Ultra-scalable GPU acceleration for Gen AI fine tuning and inferencing for large workloads with many GPUs | Next-level performance for Gen AI fine tuning and inferencing and other mixed workloads with the high-performance NVIDIA GH200 NVL2 architecture | High Frequency Trading, Monte Carlo, Agentic AI Sandbox | Large AI model training and fine-tuning |
| Rack units | 4U | 2U | 2U | 5U Direct-Liquid Cooled, 6U Air |
| Cooling | Air, Direct Liquid Cooling | Air | Air-Cooled | Air or direct-liquid cooling |
| Processor | 2P Intel® Xeon® 6 processor | NVIDIA Grace CPU and Hopper GPU in the GH200 | NVIDIA Vera CPU | 2P 5th Gen AMD EPYC™ Proceessors |
| Max memory | Up to 8TB DDR5 | Up to 60GB LPDDR5x for Grace and 288GB HBM3e for Hopper | Up to 3TB SOCAMM (Small Outline Compression Attached Memory Module) | Up to 6TB DDR5 |
| Storage | SFF, EDSFF drives | EDSFF drives | EDSFF drives | EDSFF drives |
| Management | HPE iLO 7, HPE Compute Ops Management | HPE iLO 7, monitor with HPE Compute Ops Management | HPE iLO 7, HPE Compute Ops Management | HPE iLO 6, HPE Performance Cluster Manager |
| GPU | 600W GPU and up to 8, 10 Double-Wide or 16 Single-Wide | N/A | N/A | 8x NVIDIA H200 SXM or 8x NVIDIA Blackwell (B200) |
 HPE ProLiant Compute DL320 Gen12 |  HPE ProLiant DL320 Gen11 |  HPE ProLiant Compute DL325 Gen12 |  HPE ProLiant DL325 Gen11 |  HPE ProLiant Compute DL340 Gen12 |  HPE ProLiant Compute DL340e Gen12 (enhanced storage) |  HPE ProLiant Compute DL345 Gen12 |  HPE ProLiant DL345 Gen11 |  HPE ProLiant Compute DL360 Gen12 |  HPE ProLiant DL360 Gen11 |  HPE ProLiant DL365 Gen11 |  HPE ProLiant Compute DL380 Gen12 |  HPE ProLiant DL380 Gen11 |  HPE ProLiant DL385 Gen11 |  HPE ProLiant DL560 Gen11 |  HPE ProLiant Compute DL580 Gen12 |  HPE ProLiant Compute XD230 | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Workloads | VDI, Virtualization, Containers, Hybrid Cloud | Container, Hybrid Cloud, VDI, Virtualization | Hybrid Cloud, Container, and Virtualization | Container, Hybrid Cloud, VDI, Virtualization | Hybrid Cloud, Data | Big Data, object, file, block, data analytics, content delivery, Hadoop, data lake, video surveillance, storage HCI, protection, archive, streaming | Virtualization, SDS, and Data Management | Data, Hybrid Cloud | VDI, Virtualization, Containers, Hybrid Cloud | Container, Hybrid Cloud, VDI, Virtualization | Data, Container, Hybrid Cloud, VDI, Virtualization | VDI, Virtualization, Containers, Data Management | VDI, Virtualization | VDI, Virtualization | Big Data, Data Analytics | Big Data, In-memory database, Data analytics | Manufacturing (CAE, EDA), Weather & Climate, Finance (FSI) |
| Rack units | 1U | 1U | 1U | 1U | 2U | 2U Rack | 2U | 2U | 1U | 1U | 1U | 2U | 2U | 2U | 2U | 4U | 1U |
| Cooling | Air, Closed-Loop Liquid Cooled, Direct Liquid Cooled | Air | Air, Closed-Loop Liquid Cooled, Direct Liquid Cooled | Air, Closed-Loop Liquid Cooled | Air, Direct Liquid Cooled | Air cooling with Performance Fan and Heatsink Kits | Air, Direct Liquid Cooled | Air | Air, Closed-Loop Liquid Cooled, Direct Liquid Cooled | Air, Closed-Loop Liquid Cooled, Direct Liquid Cooled | Air, Direct Liquid Cooled | Air, Direct Liquid Cooled | Air, Direct Liquid Cooled | Air, Direct Liquid Cooled | Air, Closed-Loop Liquid Cooled | Air | Air-cooled (through closed-loop liquid cooling), Direct liquid-cooled |
| Processor | 1P Intel Xeon 6 | 1P 4th or 5th Gen Intel Xeon Scalable | 1P 5th Generation AMD EPYC™ | 1P 4th or 5th Generation AMD EPYC | 1P Intel Xeon 6 | 1P Intel® Xeon® 6, up to 144 Cores | 1P 5th Generation AMD EPYC | 1P 4th or 5th Generation AMD EPYC | 2P Intel Xeon 6 processor | 2P 4th or 5th Gen Intel Xeon Scalable | 2P 4th or 5th Generation AMD EPYC | 2P Intel Xeon 6 | 2P 4th or 5th Gen Intel Xeon Scalable | 2P 4th or 5th Generation AMD EPYC | 4P 4th Gen Intel Xeon Scalable | 4P Intel Xeon 6 | 2P Intel Xeon 6900 |
| Max memory | Up to 4TB DDR5 | Up to 2TB DDR5 | Up to 6TB DDR5 | Up to 3TB DDR5 | Up to 4TB DDR5 | Up to 2TB DDR5 | Up to 6TB DDR5 | Up to 3TB DDR5 | Up to 8TB DDR5 | Up to 8TB DDR5 | Up to 6TB DDR5 | Up to 8TB DDR5 | Up to 8TB DDR5 | Up to 6TB DDR5 | Up to 16TB DDR5 | Up to 16TB DDR5 | Up to 3TB DDR5 |
| Storage | LFF, SFF, EDSFF drives | SFF, LFF, EDSFF drives | LFF, SFF, EDSFF drives | EDSFF, SFF, LFF drives | LFF, SFF, EDSFF drives | Up to 24 LFF in the front and optional up to 10 EDSFF in the rear within a 2U standard depth chassis | LFF, SFF, EDSFF drives | EDSFF, SFF, LFF drives | LFF, SFF, EDSFF drives | SFF, LFF, EDSFF drives | EDSFF, SFF drives | LFF, SFF, EDSFF drives | SFF, LFF, EDSFF drives | EDSFF, SFF, LFF drives | SFF drives | SFF, EDSFF drives | SFF, EDSFF drives |
| Management | HPE iLO 7, HPE Compute Ops Management | HPE iLO 6, HPE Compute Ops Management | HPE iLO 7, HPE Compute Ops Management | HPE iLO 6, HPE Compute Ops Management | HPE iLO 7, HPE Compute Ops Management | Included—HPE iLO 7 Standard with Intelligent Provisioning (embedded), HPE OneView Standard (requires download), Compute Ops Mgmt | HPE iLO 7, HPE Compute Ops Management | HPE iLO 6, HPE Compute Ops Management | HPE iLO 7, HPE Compute Ops Management | HPE iLO 6, HPE Compute Ops Management | HPE iLO 6, HPE Compute Ops Management | HPE iLO 7, HPE Compute Ops Management | HPE iLO 6, HPE Compute Ops Management | HPE iLO 6, HPE Compute Ops Management | HPE iLO 6, HPE Compute Ops Management | HPE iLO 7, HPE Compute Ops Management | HPE iLO, HPE Compute Ops Management, HPE Performance Cluster Manager |
| GPU | 2 Double-Wide or 4 Single-Wide | 2 Double-Wide or 4 Single-Wide | 2 Double-Wide or 4 Single-Wide | 2 Double-Wide or 4 Single-Wide | 4 Double-Wide or 6 Single-Wide | Up to 5 single-wide (SW) GPUs (restrictions apply) | 4 Double-Wide or 6 Single-Wide | 2 Double-Wide or 4 Single-Wide | 3 Single-Wide | 2 Single-Wide | 2 Double-Wide or 2 Single-Wide | 3 Double-Wide or 8 Single-Wide | 3 Double-Wide or 4 Single-Wide | 4 Double-Wide or 8 Single-Wide | N/A | N/A | |
 HPE ProLiant Compute ML350 Gen12 |  HPE ProLiant ML350 Gen11 |  HPE ProLiant ML110 Gen11 |  HPE ProLiant ML30 Gen11 |  HPE ProLiant MicroServer Gen11 | |
|---|---|---|---|---|---|
| Workloads | Edge, SMB | Edge, SMB | SMB, Edge | SMB, Remote site | SMB, Remote site |
| Rack units | 2 socket tower | 4U | Tower | Tower | Tower |
| Cooling | Air | Air | Air | Air | Air |
| Processor | 2P Intel Xeon 6 | 2P 4th or 5th Gen Intel Xeon Scalable | 1P 4th or 5th Gen Intel Xeon Scalable | 1P Intel Xeon 6, and Intel Xeon E-2400 | 1P Intel Xeon 6, Intel Xeon E-2400, and Pentium® |
| Max memory | Up to 8TB DDR5 | Up to 8TB DDR5 | Up to 1.5 TB | Up to 128 GB | Up to 128 GB |
| Storage | LFF, SFF, EDSFF drives | EDSFF, SFF, LFF | LFF, SFF drives | LFF, SFF drives | LFF, SFF drives |
| Management | HPE iLO 7, HPE Compute Ops Management | HPE iLO 6, HPE Compute Ops Management | HPE iLO 6, HPE Compute Ops Management | HPE iLO 6, HPE Compute Ops Management | HPE iLO 6, HPE Compute Ops Management |
| GPU | 4 Double-Wide or 8 Single-Wide | 4 Double-Wide or 8 Single-Wide | 1 Double-Wide or 2 Single-Wide | 1 Single-Wide | 1 Single-Wide |
| HPE ProLiant MicroServer |  HPE ProLiant ML30 | HPE ProLiant ML110 | HPE ProLiant ML350 |  HPE ProLiant DL20 |  HPE ProLiant DL110 |  HPE ProLiant DL145 |  HPE ProLiant EL8000s |  HPE ProLiant Compute EL9000 |  HPE ProLiant Compute EL2000 | |
|---|---|---|---|---|---|---|---|---|---|---|
| Edge workloads | Small Business IT | SMB, Remote Office, File/Web/Email Server, Point of Sale, entry AI | SMB, virtualization, databases, and office productivity, entry AI | SMB and business-critical workloads—ERP, CRM, databases, virtualization and AI | SMB, Remote Office, File/Web/Email Server, Point of Sale, entry AI | Telco, vRAN, ORAN, Centralized/Distributed RAN | AI inference, Virtualization, Data analytics, Industrial automation, Vision analytics | Media streaming, AI inference, industrial IoT | Macro RAN sites | AI, data processing, automation, video analytics |
| Form factor | Ultra-compact | MicroTower | Mid Tower | Performance Tower | 1U Rack | 1U Rack | Tabletop, Rack (2U) and Cabinet | 2U Ruggedized | 2U 2-Node Ruggedized | 2 U chassis supports up to two (2) HPE Compute EL220 (1U) or one (1) EL240 (2U) servers |
| Processor | Intel® Xeon® 6300-series, Intel® Xeon® E and Intel® Pentium® | Intel® Xeon® E processors up to 8 cores | 4th and 5th Gen Intel® Xeon® Scalable Processors, up to 32 cores | Intel® Xeon® 6700/6500 P-series processors, up to 86 P-cores per socket | Intel® Xeon® 6300 series, Intel® Xeon® E and Intel® Pentium® Processors up to 8 cores | Intel® Xeon® 6 SoC processors with Intel® vRAN Boost | AMD EPYC 8005 Series processors up to 84 cores, 4th Generation AMD EPYC™ processors up to 64 cores | 4th Gen Intel® Xeon® Scalable processor (SPR), 32 cores | Intel® Xeon® 6 SoC processors with Intel® vRAN Boost, 72 cores | Intel Xeon 6 128 core (EL220) 144 core (EL240) |
| Max memory | Up to 128 GB DDR5 ECC | Up to 128 GB DDR5 | Up to 1.5TB DDR5 | Up to 8TB DDR5 | Up to 128GB | Up to 512 GB DDR5 | Up to 768GB DDR5 | Up to 4TB DDR5 | Up to 1TB DDR5 | 2TB DDR5 |
| Storage | 4 LFF NHP SATA HDD or 4 SFF NHP SSD | 4LFF or 8SFF, HPE NS204i-u Gen11 NVMe Hot Plug | 4 to 8 LFF SAS/SATA or 8 to 16 SFF SAS/SATA HDD/SDD | Up to 12x EDSFF or 8x SFF or 4xLFF drives | Up to 4+2 Hot Plug SFF or 2 LFF | 2x M.2 drives are supported on the Motherboard | 2 SFF or 6 EDSFF SATA/NVMe | 8 M.2 NVMe | 2 M.2 NVMe | 2 M.2 NVMe + 4 EDSFF |
| Management | HPE iLO 6, OneView, HPE Compute Ops Management | HPE iLO 6, HPE Compute Ops Management | HPE iLO 6 | HPE iLO 7 | HPE iLO 6, OneView, HPE Compute Ops Management | Included - HPE iLO 7 Standard with Intelligent Provisioning (embedded), HPE OneView Standard (requires download), HPE Compute Ops Management | HPE iLO 6, HPE Compute Ops Management | HPE iLO 6 | HPE iLO 7 | HPE iLO 7 |
| GPU | - | Up to one single-wide GPU | Up to 2 single-wide GPU | Up to 8 single-wide or 4 double-wide GPUs | Optional | Up to (2) Half-Height Half-Length GPUs or up to (2) 100W In-Line Accelerators | Up to one double-wide or 3 single-wide GPUs | Optional | Up to 2 HHHL GPUs | 2 single-wide/ 1 double-wide GPU (EL240 only) |
Our partners
HPE ProLiant Compute savings estimator
Your aging servers may still be working—but at what cost?
Modernize your data center by refreshing to next-gen HPE ProLiant Compute to unlock up to 7:1 server consolidation and up to 65% power savings.
Discover your savings potential in less than two minutes.
FAQs
What are HPE ProLiant Compute servers?
HPE ProLiant Compute servers are enterprise servers designed to support modern workloads across data centers, hybrid cloud environments, remote offices, edge locations, and AI infrastructure. They provide a secure, scalable compute foundation for business applications, virtualized workloads, data-intensive applications, and GPU-accelerated workloads. HPE ProLiant Compute helps organizations modernize IT, improve efficiency, simplify operations, and support changing workload demands from edge to cloud.
What are the key features of HPE ProLiant Compute servers?
HPE ProLiant Compute servers include features designed to improve security, performance, efficiency, and manageability. Depending on the model, capabilities may include HPE iLO server management, HPE Compute Ops Management, Intel and AMD processor options, NVIDIA GPU acceleration (including DL394 configurations), DDR5 memory, PCIe Gen5, air or liquid cooling options, and configurations for AI, virtualization, hybrid cloud, SMB, edge, and enterprise workloads.
What are the benefits of using HPE ProLiant Compute servers?
HPE ProLiant Compute servers help organizations modernize aging infrastructure, reduce operational risk, improve workload performance, and simplify server management. They support consolidation by running more workloads on fewer servers, reducing power and cooling demands, and improving IT productivity through automation and centralized management. HPE ProLiant Compute also gives organizations flexible options for data center, edge, AI, virtualization, and small business environments.
How do HPE ProLiant Compute servers improve energy efficiency?
HPE ProLiant Compute servers can improve energy efficiency by delivering higher performance per watt, supporting server consolidation, and offering efficient cooling options for demanding workloads. By refreshing older servers with newer HPE ProLiant Compute models, organizations may reduce the number of physical servers needed, with up to 7:1 server consolidation compared to HPE ProLiant Gen10, lower power and cooling requirements, and up to 65% power savings compared to HPE ProLiant Gen10. Select models also support liquid cooling for high-performance and AI workloads.
What kind of HPE ProLiant Compute server do I need for AI and machine learning?
The right HPE ProLiant Compute server for AI and machine learning depends on workload size and type. Smaller AI inference, edge AI, and entry-level acceleration may use select rack, tower, or edge models with GPU options. Larger generative AI, model training, fine-tuning, and high-performance AI workloads typically require AI-optimized servers using NVIDIA RTX Pro GPUs and other GPU acceleration options.
What is the difference between HPE ProLiant Compute DL, ML, and XD servers?
HPE ProLiant Compute DL, ML, and XD servers are designed for different deployment needs. DL servers are rack-optimized systems built for data center, virtualization, hybrid cloud, and general enterprise workloads. ML servers are tower or rack-convertible systems often used for small business, edge, remote office, and expandable mixed-workload environments. XD servers are purpose-built for dense, demanding workloads such as generative AI, model training, data analytics, and GPU-accelerated computing
What is the difference between HPE ProLiant Compute Gen11 and Gen12 servers?
HPE ProLiant Compute Gen11 and Gen12 servers both support modern enterprise workloads, but Gen12 servers are designed for the next generation of performance, security, efficiency, and automation. Depending on the model, Gen12 systems may include newer processors, the newest version of HPE iLO with enhanced security features, expanded memory and storage configurations, PCIe Gen5 support, liquid cooling options, and stronger support for demanding workloads from VDI to AI. Gen11 remains a strong option for many current infrastructure needs.
Where can I buy HPE ProLiant Compute servers or get a price quote?
HPE ProLiant Compute servers are available through HPE, authorized HPE resellers, and enterprise technology partners. Businesses can explore purchasing options through the HPE store or work with a reseller to configure the right server based on workload, processor, memory, storage, GPU, cooling, support, and deployment requirements. For specialized configurations such as rack servers with NVIDIA GPUs or liquid cooling, request a quote or speak with an HPE sales representative or authorized partner.
HPE ProLiant Compute resources
-
SoftwareReduce cost and complexity of virtualized workloads
HPE ProLiant Compute combined with HPE Morpheus Software—VM Essentials delivers a compelling solution for organizations working to simplify management of their virtual environments. Provision and manage both KVM and VMware-based virtual machines from a single interface, simplifying virtualization management and reducing costs.
Try it free for 30 days -
BrochureModernize your data center with flexible server design
Transform how you manage compute with flexible server architecture built for evolving workloads. HPE ProLiant Compute Gen12 servers use a modular design to reduce complexity, speed innovation, and extend the life of your infrastructure.
Explore next-gen infrastructure
