Compute servers HPE ProLiant Compute
Propel your business forward with next-gen HPE ProLiant Compute servers, purpose-built for today's hybrid world. Modernize confidently with built-in security, AI-driven automation, and energy-efficient performance. Simplify operations, reduce risks, and gain real-time value from edge to cloud.
HPE ProLiant Compute savings estimator
Your aging servers may still be working—but at what cost?
Modernize your data center by refreshing to next-gen HPE ProLiant Compute to unlock up to 7:1 server consolidation and up to 65% power savings.
Discover your savings potential in less than two minutes.
Our customers
Why modernize
Enhance innovation, efficiency, and security with a modern infrastructure.
Safeguard every phase of the server lifecycle now and for the future
Industry-leading HPE iLO Silicon Root of Trust delivers a security foundation embedded within the server hardware for multi-layered protection and enhanced physical and digital intrusion resistance.
Simplify manageability across distributed computing environments
Simplify server lifecycle operations across complex, distributed environments with AI-driven insights, automation, and secure cloud-based management, enabling faster updates and proactive issue resolution.
Explore the HPE ProLiant Compute portfolio
- AI servers
- 8-GPU Servers
- Rack
- Tower
- Edge servers
 HPE ProLiant Compute DL380a Gen12 |  HPE ProLiant Compute DL380a Gen11 |  HPE ProLiant Compute DL384 Gen12 |  HPE ProLiant Compute XD685 | |
|---|---|---|---|---|
| Workloads | Ultra-scalable GPU acceleration for Gen AI fine tuning and inferencing for large workloads with many GPUs | Gen AI fine tuning and inferencing | Next-level performance for Gen AI fine tuning and inferencing and other mixed workloads with the high-performance NVIDIA GH200 NVL2 architecture | Large AI model training and fine-tuning |
| Rack units | 4U | 2U | 2U | 5U Direct-Liquid Cooled, 6U Air |
| Cooling | Air, Direct Liquid Cooling | Air | Air | Air or direct-liquid cooling |
| Processor | 2P Intel® Xeon® 6 processor | 2P 4th or 5th Gen Intel Xeon Scalable Processors | NVIDIA Grace CPU and Hopper GPU in the GH200 | 2P 5th Gen AMD EPYC™ Proceessors |
| Max memory | Up to 8TB DDR5 | Up to 3TB DDR5 | Up to 60GB LPDDR5x for Grace and 288GB HBM3e for Hopper | Up to 6TB DDR5 |
| Storage | SFF, EDSFF drives | EDSFF, SFF drives | EDSFF drives | EDSFF drives |
| Management | HPE iLO 7, HPE Compute Ops Management | HPE iLO 6, HPE Compute Ops Management | HPE iLO 7, monitor with HPE Compute Ops Management | HPE iLO 6, HPE Performance Cluster Manager |
| GPU | 600W GPU and up to 8, 10 Double-Wide or 16 Single-Wide | 4 Double-Wide or 8 Single-Wide | N/A | 8x NVIDIA H200 SXM or 8x NVIDIA Blackwell (B200) |
 HPE ProLiant Compute XD685 |  HPE Compute XD690 |  HPE Cray XD670 | |
|---|---|---|---|
| Workloads | Large AI model training and fine-tuning | Large AI model training and fine-tuning | Large AI model training and fine-tuning |
| Rack units | 5U Direct-Liquid Cooled (DLC) , 6U Air-cooled | 10U | 5U |
| Cooling | Air or direct-liquid cooling | Air cooling | Air or direct-liquid cooling |
| Processor | 2P 5th Gen AMD EPYC™ Proceessors | 2P Intel® Xeon® 6 processors | 2P 5th Gen Intel Xeon Scalable processors |
| Management | Server: HPE iLO 6. Cluster: HPE Performance Cluster Manager (HPCM) | Server: BMC, Redfish APIs, 1GbE LAN . Cluster: HPCM | Server: BMC, Redfish APIs, 1GbE LAN . Cluster: HPE Performance Cluster Manager |
| GPU | 8x NVIDIA H200 SXM (air or DLC) , or 8x NVIDIA Blackwell B200 (DLC) , or 8x NVIDIA Blackwell Ultra (HGX B300) (DLC), or 8x AMD Instinct MI355X (DLC) | 8 X NVIDIA Blackwell Ultra (HGX B300) air-cooled | 8X NVIDIA H200 SXM air or liquid cooled |
 HPE ProLiant Compute DL320 Gen12 |  HPE ProLiant DL320 Gen11 |  HPE ProLiant Compute DL325 Gen12 |  HPE ProLiant DL325 Gen11 |  HPE ProLiant Compute DL340 Gen12 |  HPE ProLiant Compute DL345 Gen12 |  HPE ProLiant DL345 Gen11 |  HPE ProLiant Compute DL360 Gen12 |  HPE ProLiant DL360 Gen11 |  HPE ProLiant DL365 Gen11 |  HPE ProLiant Compute DL380 Gen12 |  HPE ProLiant DL380 Gen11 |  HPE ProLiant DL385 Gen11 |  HPE ProLiant DL560 Gen11 |  HPE ProLiant Compute DL580 Gen12 |  HPE ProLiant Compute XD230 | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Workloads | VDI, Virtualization, Containers, Hybrid Cloud | Container, Hybrid Cloud, VDI, Virtualization | Hybrid Cloud, Container, and Virtualization | Container, Hybrid Cloud, VDI, Virtualization | Hybrid Cloud, Data | Virtualization, SDS, and Data Management | Data, Hybrid Cloud | VDI, Virtualization, Containers, Hybrid Cloud | Container, Hybrid Cloud, VDI, Virtualization | Data, Container, Hybrid Cloud, VDI, Virtualization | VDI, Virtualization, Containers, Data Management | VDI, Virtualization | VDI, Virtualization | Big Data, Data Analytics | Big Data, In-memory database, Data analytics | Manufacturing (CAE, EDA), Weather & Climate, Finance (FSI) |
| Rack units | 1U | 1U | 1U | 1U | 2U | 2U | 2U | 1U | 1U | 1U | 2U | 2U | 2U | 2U | 4U | 1U |
| Cooling | Air, Closed-Loop Liquid Cooled, Direct Liquid Cooled | Air | Air, Closed-Loop Liquid Cooled, Direct Liquid Cooled | Air, Closed-Loop Liquid Cooled | Air, Direct Liquid Cooled | Air, Direct Liquid Cooled | Air | Air, Closed-Loop Liquid Cooled, Direct Liquid Cooled | Air, Closed-Loop Liquid Cooled, Direct Liquid Cooled | Air, Direct Liquid Cooled | Air, Direct Liquid Cooled | Air, Direct Liquid Cooled | Air, Direct Liquid Cooled | Air, Closed-Loop Liquid Cooled | Air | Air-cooled (through closed-loop liquid cooling), Direct liquid-cooled |
| Processor | 1P Intel Xeon 6 | 1P 4th or 5th Gen Intel Xeon Scalable | 1P 5th Generation AMD EPYC™ | 1P 4th or 5th Generation AMD EPYC | 1P Intel Xeon 6 | 1P 5th Generation AMD EPYC | 1P 4th or 5th Generation AMD EPYC | 2P Intel Xeon 6 processor | 2P 4th or 5th Gen Intel Xeon Scalable | 2P 4th or 5th Generation AMD EPYC | 2P Intel Xeon 6 | 2P 4th or 5th Gen Intel Xeon Scalable | 2P 4th or 5th Generation AMD EPYC | 4P 4th Gen Intel Xeon Scalable | 4P Intel Xeon 6 | 2P Intel Xeon 6900 |
| Max memory | Up to 4TB DDR5 | Up to 2TB DDR5 | Up to 6TB DDR5 | Up to 3TB DDR5 | Up to 4TB DDR5 | Up to 6TB DDR5 | Up to 3TB DDR5 | Up to 8TB DDR5 | Up to 8TB DDR5 | Up to 6TB DDR5 | Up to 8TB DDR5 | Up to 8TB DDR5 | Up to 6TB DDR5 | Up to 16TB DDR5 | Up to 16TB DDR5 | Up to 3TB DDR5 |
| Storage | LFF, SFF, EDSFF drives | SFF, LFF, EDSFF drives | LFF, SFF, EDSFF drives | EDSFF, SFF, LFF drives | LFF, SFF, EDSFF drives | LFF, SFF, EDSFF drives | EDSFF, SFF, LFF drives | LFF, SFF, EDSFF drives | SFF, LFF, EDSFF drives | EDSFF, SFF drives | LFF, SFF, EDSFF drives | SFF, LFF, EDSFF drives | EDSFF, SFF, LFF drives | SFF drives | SFF, EDSFF drives | SFF, EDSFF drives |
| Management | HPE iLO 7, HPE Compute Ops Management | HPE iLO 6, HPE Compute Ops Management | HPE iLO 7, HPE Compute Ops Management | HPE iLO 6, HPE Compute Ops Management | HPE iLO 7, HPE Compute Ops Management | HPE iLO 7, HPE Compute Ops Management | HPE iLO 6, HPE Compute Ops Management | HPE iLO 7, HPE Compute Ops Management | HPE iLO 6, HPE Compute Ops Management | HPE iLO 6, HPE Compute Ops Management | HPE iLO 7, HPE Compute Ops Management | HPE iLO 6, HPE Compute Ops Management | HPE iLO 6, HPE Compute Ops Management | HPE iLO 6, HPE Compute Ops Management | HPE iLO 7, HPE Compute Ops Management | HPE iLO, HPE Compute Ops Management, HPE Performance Cluster Manager |
| GPU | 2 Double-Wide or 4 Single-Wide | 2 Double-Wide or 4 Single-Wide | 2 Double-Wide or 4 Single-Wide | 2 Double-Wide or 4 Single-Wide | 4 Double-Wide or 6 Single-Wide | 4 Double-Wide or 6 Single-Wide | 2 Double-Wide or 4 Single-Wide | 3 Single-Wide | 2 Single-Wide | 2 Double-Wide or 2 Single-Wide | 3 Double-Wide or 8 Single-Wide | 3 Double-Wide or 4 Single-Wide | 4 Double-Wide or 8 Single-Wide | N/A | N/A | |
 HPE ProLiant Compute ML350 Gen12 |  HPE ProLiant ML350 Gen11 |  HPE ProLiant ML110 Gen11 |  HPE ProLiant ML30 Gen11 |  HPE ProLiant MicroServer Gen11 | |
|---|---|---|---|---|---|
| Workloads | Edge, SMB | Edge, SMB | SMB, Edge | SMB, Remote site | SMB, Remote site |
| Rack units | 2 socket tower | 4U | Tower | Tower | Tower |
| Cooling | Air | Air | Air | Air | Air |
| Processor | 2P Intel Xeon 6 | 2P 4th or 5th Gen Intel Xeon Scalable | 1P 4th or 5th Gen Intel Xeon Scalable | 1P Intel Xeon 6, and Intel Xeon E-2400 | 1P Intel Xeon 6, Intel Xeon E-2400, and Pentium® |
| Max memory | Up to 8TB DDR5 | Up to 8TB DDR5 | Up to 1.5 TB | Up to 128 GB | Up to 128 GB |
| Storage | LFF, SFF, EDSFF drives | EDSFF, SFF, LFF | LFF, SFF drives | LFF, SFF drives | LFF, SFF drives |
| Management | HPE iLO 7, HPE Compute Ops Management | HPE iLO 6, HPE Compute Ops Management | HPE iLO 6, HPE Compute Ops Management | HPE iLO 6, HPE Compute Ops Management | HPE iLO 6, HPE Compute Ops Management |
| GPU | 4 Double-Wide or 8 Single-Wide | 4 Double-Wide or 8 Single-Wide | 1 Double-Wide or 2 Single-Wide | 1 Single-Wide | 1 Single-Wide |
| HPE ProLiant MicroServer |  HPE ProLiant ML30 | HPE ProLiant ML110 | HPE ProLiant ML350 |  HPE ProLiant DL20 |  HPE ProLiant DL110 |  HPE ProLiant DL145 | |
|---|---|---|---|---|---|---|---|
| Edge workloads | Small Business IT | SMB, Remote Office, File/Web/Email Server, Point of Sale, entry AI | SMB, virtualization, databases, and office productivity, entry AI | SMB and business-critical workloads - ERP, CRM, databases, virtualization and AI | SMB, Remote Office, File/Web/Email Server, Point of Sale, entry AI | Telco, vRAN, ORAN, Centralized/Distributed RAN | AI inference, Virtualization, Data analytics, Industrial automation, Vison analytics |
| Form factor | Ultra-compact | MicroTower | Mid Tower | Performance Tower | 1U Rack | 1U Rack | Tabletop, Rack (2U) and Cabinet |
| Processor | Intel® Xeon® 6300-series, Intel® Xeon® E and Intel® Pentium® | Intel® Xeon® E processors up to 8 cores | 4th and 5th Gen Intel® Xeon® Scalable Processors, up to 32 cores | Intel® Xeon® 6700/6500 P-series processors, up to 86 P-cores per socket | Intel® Xeon® 6300 series, Intel® Xeon® E and Intel® Pentium® Processors up to 8 cores | Intel® Xeon® 6 SoC processors with Intel® vRAN Boost | 4th Generation AMD EPYC™ processors (up to 64 cores) |
| Max memory | Up to 128 GB DDR5 ECC | Up to 128 GB DDR5 | Up to 1.5TB DDR5 | Up to 8TB DDR5 | Up to 128GB | Up to 512 GB DDR5 | Up to 768GB |
| Storage | 4 LFF NHP SATA HDD or 4 SFF NHP SSD | 4LFF or 8SFF, HPE NS204i-u Gen11 NVMe Hot Plug | 4 to 8 LFF SAS/SATA or 8 to 16 SFF SAS/SATA HDD/SDD | Up to 12x EDSFF or 8x SFF or 4xLFF drives | Up to 4+2 Hot Plug SFF or 2 LFF | 2x M.2 drives are supported on the Motherboard | 2 SFF or 6 EDSFF SATA/NVMe |
| Management | HPE iLO 6, OneView, Compute Ops Mgmt | HPE iLO 6, Compute Ops Mgmt | iLO 6 | iLO 7 | HPE iLO 6, OneView, Compute Ops Mgmt | Included - HPE iLO7 Standard with Intelligent Provisioning (embedded), HPE OneView Standard (requires download), Compute Ops Mgmt | HPE iLO 6, Compute Ops Mgmt |
| GPU | - | Up to one single-wide GPU | Up to 2 single-wide GPU | Up to 8 single-wide or 4 double-wide GPUs | Optional | Up to (2) Half-Height Half-Length GPUs or up to (2) 100W In-Line Accelerators | Up to one double-wide or 3 single-wide GPUs |
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FAQs
What are HPE ProLiant Compute servers?
HPE ProLiant Compute servers are the trusted foundation for modern IT—designed to help organizations run their businesses with confidence, efficiency, and agility. They provide a secure, enterprise grade compute platform that enables organizations to protect critical data and operations, scale performance to meet evolving business demands, and modernize infrastructure without adding complexity, all while improving cost efficiency and sustainability. HPE ProLiant Compute blends strong security, AI-powered operations, and an edge-to-data-center lineup to turn IT from a reactive cost into a strategic driver of resilience, growth, and innovation.
What are the features of HPE ProLiant Compute servers?
HPE ProLiant Compute servers deliver next-level security, performance, and efficiency. Key features include multi-layered protection with a secure enclave, FIPS 140-3 Level 3 readiness, quantum-resistant firmware, and a trusted supply chain. They offer AI-optimized platforms, direct liquid cooling, automated carbon reporting, and unified management with predictive AI insights, supporting seamless operations across multi-vendor environments and enabling advanced workloads like AI, enterprise workloads, and edge computing.
What are the benefits of using HPE ProLiant Compute servers?
HPE ProLiant Compute servers help organizations reduce business risk, lower operating costs, and increase IT productivity by providing a trusted compute foundation that protects critical data and uptime, enables more work to be done with fewer servers and less power, and simplifies day-to-day operations across data center and edge environments, allowing IT teams to respond faster, make better decisions with greater visibility, support new workloads with confidence, and free up budget and staff time to focus on innovation rather than infrastructure maintenance—all of which contributes to improved resilience, scalability, and long-term return on investment for the business.
What are the latest models of HPE ProLiant Compute servers?
Gen11 and Gen12 feature the latest AMD and Intel processors including high performance PCIe5, DDR 5 fast memory and support for the latest NVIDIA GPUs.
What are the best HPE ProLiant Compute server models for small businesses?
HPE ProLiant MicroServer is ultra-compact and ideal for small edge sites, ML30 for entry tower needs, ML110 for growing virtualization and consolidation, DL20 for compact rack or edge environments and compact and ruggedized DL145 for harsh environments and industry specific workloads, and ML350 for SMBs requiring maximum expandability, resilience, and long-term scalability.
Can I upgrade my HPE ProLiant Compute server?
Check the HPE ProLiant Compute savings estimator and contact your local reseller for information on how to upgrade your servers.
Where can I buy HPE ProLiant Compute servers?
Visit the HPE store to learn more about buying HPE ProLiant Compute servers or visit your local reseller.
HPE ProLiant Compute resources
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Reduce cost and complexity of virtualized workloads
HPE ProLiant Compute combined with HPE Morpheus VM Essentials delivers a compelling solution for organizations working to simplify management of their virtual environments. Provision and manage both KVM and VMware-based virtual machines from a single interface, simplifying virtualization management and reducing costs.
Try it free for 30 days -
Modernize your data center with flexible server design
Transform how you manage compute with flexible server architecture built for evolving workloads. HPE ProLiant Compute Gen12 servers use a modular design to reduce complexity, speed innovation, and extend the life of your infrastructure.
Explore next-gen infrastructure
