HPE ProLiant Compute ML350 Gen12

The ML350 Gen12 is a performance optimized 2P tower server for edge and SMB environments. It is equipped to handle diverse workloads such as IT infrastructure, data management, VDI, and ERP/CRM.

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HPE ProLiant Compute ML350 Gen12.
HPE ProLiant Compute ML350 Gen12.

HPE ProLiant Compute ML350 Gen12

The HPE ProLiant Compute ML350 Gen12 is a durable 2‑socket tower (rack-convertible) server that delivers high compute, security, reliability, and expansion for varied deployments. Powered by Intel® Xeon® 6700/6500 P‑series processors (up to 86 P‑cores per socket) and up to 8 TB DDR5‑6400 memory, it handles demanding, mixed workloads.

An HPE‑exclusive ASIC implements a Silicon Root of Trust, binding firmware to a processor-specific fingerprint that must match before boot, protecting firmware integrity.

Ideal for IT infrastructure, data management, VDI, ERP/CRM—scale and adapt to accelerate business growth.

What's new

  • Powered by Intel® Xeon® 6700 and 6500 series with P-cores; up to 86 P-cores per socket (172 P-cores per server), 350W (TDP); increased memory bandwidth to 6400 MT/s2, up to 8TB DDR5 memory capacity.
  • Supports ultra-high SSD performance with NVMe x4 and EDSFF drive cages and allows mixed dual-mode LFF and tri-mode SFF drive cages as hybrid storage optimization solution.
  • Provides up to 24 NVMe drives with PCIe Gen5 x2 bandwidth to have maximum storage capacity with balanced performance solution.
  • Supports NVIDIA RTX Pro 4500 Blackwell SE 32GB or NVIDIA RTX A1000 8GB.

Product solutions

Powerful and versatile compute with storage flexibility—The HPE ProLiant ML350 Gen12

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Technical specifications

  • Top workloads

    Edge, SMB


  • Form factory

    2 socket tower


  • Cooling

    Air


  • Processor

    2P Intel Xeon 6


  • GPU

    4 Double-Wide or 8 Single-Wide


  • Max memory

    Up to 8TB DDR5


  • Storage

    LFF, SFF, EDSFF drives


  • Management

    HPE iLO 7, HPE Compute Ops Management 


Resources

HPE Compute Security

Safeguard against digital and physical threats with next-level security.

HPE ProLiant Compute Solutions

Optimize performance and efficiency in the data center and at the edge, to power tailored workloads from VDI to AI.

HPE ProLiant Compute AI Solutions

Unlock more value from your data and accelerate AI outcomes that deliver insights and innovation.

HPE Tech Care Service for HPE ProLiant Compute

Gain expedited access to trusted experts with deep, product-specific knowledge to get the answers you need, fast!

Financing and IT Lifecycle Services

Remove budget barriers, get the latest tech and accelerate innovation with tailored financing and IT lifecycle services.

Related items

HPE ProLiant Compute Servers

Simplify operations, reduce risks, and gain real-time value from edge to cloud.

HPE Integrated Lights-Out (iLO)

Securely configure, monitor, and update your HPE ProLiant servers with industry-leading Silicon Root of Trust.

HPE Compute Ops Management

Seamlessly monitor, manage, and gain visibility of your distributed compute environment with a cloud-native solution.

HPE Services for Compute

Benefit from HPE experts and world-class services professionals to help exceed your business expectations.

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